Fiber can help gut bacteria produce a metabolite
Researchers from Yale have discovered a strong link between diet, gut bacteria, and lupus, an autoimmune disease. When animal models were fed a high-fiber diet, it enriched the good bacteria within their intestines, and suppressed the growth of bacteria that would lead to an autoimmune disease. This suggests a diet high in fiber could help prevent or ease lupus.
A diet rich in fiber can help gut bacteria produce a metabolite called propionate. In animal models, researchers found this decreased the consequences of high blood pressure such as vascular damage, damage of the heart, abnormal enlargement, and abnormal heart rhythms. This helps increase the survival rates. This further supports that a diet rich in fiber helps prevent cardiovascular diseases.
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Western lifestyle is linked to various inflammatory conditions such as autoimmune and metabolic diseases, driven by changes in diet and gut microbial composition, as suggested by the hygiene hypothesis. A Western diet is characterized by a low-fiber and high-fat composition, which affects gut microbial communities and immune functions, and promotes disease. Gut microbiota and their metabolites mediate mucosal and systemic immune responses, and alterations in its composition have been linked to multiple autoimmune disorders
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