Ginsenosides May Prevent Lung Cancer Metastasis
A study published in the Journal of Ginseng Research has found that ginsenosides Rk1 and Rg5 may significantly suppress lung cancer metastasis. They may inhibit various processes related to cancer metastasis, and have other anti-cancer effects. These ginsenosides can be found in various types of ginseng, including American ginseng.
Lung cancer is one of the leading causes for mortality. Non-small cell lung carcinoma (NSCLC) is the most common lung malignancy and contributes to approximately 80% of all lung cancers [, , ]. One of the major challenges associated with lung cancer management is cancer metastasis. Even with advancements in cancer treatment and management, there are no effective treatments for lung cancer metastasis . Therefore, understanding the metastasis mechanisms is necessary for successful treatment of NSCLC.
Panax ginseng Meyer, the root of P. ginseng has been used as functional food and herbal medicine for thousands of years worldwide, especially in Korea and China, owing to its medicinal properties [16,17]. The biologically active components of ginseng are called ginsenosides. For example, it has been recently evaluated for the antiarthritic effects of Rg3, Rk1, and Rg5, using a collagen-induced mouse arthritis model.
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